The altered permeability of blood vessels permits the passage of large molecules through capillary walls.The blood vessels appear to weep, a reflection of the Latin origins of the word exudate. Wound Healing Wound healing occurs in three overlapping phases: the inflammatory phase, the proliferative phase and the remodeling phase.
The neutrophils and macrophages in the fluid go to the wound to destroy bacteria and debris.The macrophages are also a source of cytokines, growth factors and proteolytic enzymes necessary for the wound to heal.The proliferation phase is characterized by the formation of granulation tissue.During the remodeling or maturation phase, the wound closes, and scar tissue forms.Objectives: The purpose of this article is to educate nurse practitioners about the role wound exudate in wound healing.After reading this article and its supporting material, the nurse practitioner should be able to do the following: Wound bed preparation provides a systematic path to wound healing, and one of the primary components of this preparation is moisture.
A balance in moisture is critical to wound healing, but the exact amount of exudate necessary to promote wound healing is unknown.
If a wound contains insufficient moisture, moisture can be added - most often through the use of specialized dressings.
But too much moisture makes the wound too wet, and in such cases management often becomes focused on methods to contain the excess moisture rather than determine the cause.
This article discusses wound exudate and methods to monitor and assess it accurately. Exudate is fluid that filters from the circulatory system into areas of the body that are inflamed.
Inflammation leads to an increase in blood vessel dilatation and permeability with extracellular fluid formation, resulting in increased production of exudate.
Wound exudate is protein-rich and cell-rich wound fluid that seeps out of blood vessels as a result of inflammation and is deposited in nearby tissues.